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| Scientific Papers on NMR (Nuclear Magnetic Resonance) |
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A Single Scan, Three-Dimensional, Gradient Accelerated Homonuclear J-COSY Experiment
Michael L. Woodley, T. Adrian Carpenter and Laurance D. Hall
Journal Of Magnetic Resonance, Series A, Vol. 106, 147 (1994)
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"Decoupled" Proton NMR Spectra
Michael L. Woodley and Ray Freeman
Journal Of Magnetic Resonance, Series A, Vol. 109, 103 (1994)
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Elimination of Spin-Spin Splittings from High-Resolution Proton NMR Spectra
Michael L. Woodley and Ray Freeman
Journal Of Magnetic Resonance, Series A, Vol. 111, 225 (1994)
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A New Scheme for Two-Dimensional NMR Shift Correlation
Michael L. Woodley and Ray Freeman
Journal Of The American Chemical Society, Vol. 117, No. 22, 6151 (1995)
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Recognition and Clarification of Cross Peaks in Crowded Two-Dimensional Correlation Spectra
Michael L. Woodley and Ray Freeman
Journal Of Magnetic Resonance, Series A, Vol. 118, 39 (1996)
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| What is NMR? |
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NMR exploits the quantum mechanical intrinsic angular momentum and magnetic moment of certain nuclei to reveal information about the environments of the nuclei's parent atoms within complex molecules. Wikipedia explains it well.
The trick is to align the nuclear magnetic moments in a very strong and fixed magnetic field, to then perturb them with RF pulses and measure the RF emitted as the nuclear magnetic moments gracefully realign with the fixed field.
This gives the individual resonant frequencies of the different nuclei in the different atoms in a molecule and reveals information about each atom's disposition within the molecule and about proximities to and interactions with neighbouring atoms.
To do NMR you need an enormous superconducting magnet and a lot of liquid helium.
You also need a great deal of computing power and an arsenal of data processing techniques to analyse large multi-dimensional data sets.
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| An 18.8 Tesla NMR Magnet |
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